A study published in the peer-reviewed journal Pharmaceutical has shown that the phytochemical 3,3-diindolylmethane (DIM) derived from cruciferous vegetables has broken down the biofilms protecting two different important pathogens, including Acinetobacter baumannii and Pseudomonas aeruginosa. Thus, increasing their eradication rates by 65% and 70%, respectively. When combined with antibiotics, the eradication rate jumped up to 94%. 

Antibiotic-resistant bacterial pathogens are increasingly playing a role in rising illness and preventing wound healing, especially in hospitals. While more and more pathogens have developed biofilms that protect them from being eradicated by antibiotics, fewer classes of antibiotics are being developed. 

Dr. Karina Golberg and her team, together with Prof. Robert Marks, all members of the Avram and Stella Goldstein-Goren Department of Biotechnology Engineering at BGU, chronicled their findings and revealed that when they introduced DIM into an infected wound, it sped up the healing process significantly. Prof. Ariel Kushmaro, Department of Biotechnology Engineering at BGU, added that the findings show promise for other avenues of research in addition to known classes of antibiotics. 

(Source: https://health.economictimes.indiatimes.com/news/diagnostics/phytochemical-derived-from-vegetables-might-be-the-solution-to-antibiotic-resistant-pathogens/93755915 )